We are proud to contribute to a newly published study in Cellular and Molecular Life Sciences led by Z. Cvackova (Institute of Molecular Genetics, Prague), in collaboration with partners from Goethe University Frankfurt and others. The study reveals how specific retinitis pigmentosa-linked mutations impair the RNA helicase activity of SNRNP200 and alter RNA binding of PRPF8, offering new insights into the splicing defects underlying retinal degeneration. Our lab supported this effort by providing expertise in protein engineering and biochemical analysis. Congratulations to our collaborators and the entire research team on this excellent work!
