ACS Pharmacol Transl Sci manuscript!


Congratulations to Gargi on her first first-author manuscript published in ACS Pharmacol Transl Sci! Here we describe the engineering and biophysical and biological characterization of bispecific T-cell engagers (BiTEs) that enable targeting PSMA-positive tumor cells by host T lymphocytes. Our 5D3-αCD3 BiTE can be viewed as a candidate molecule for the development of immunotherapeutic modalities targeting prostate cancer. Great job Gargi and you are a step closer to your PhD defense!