In collaboration with the Laboratory of Transgenic Models of Diseases and the Czech Centre for Phenogenomics, we have contributed to the development of a novel approach for multistep allelic conversion in mouse pre-implantation embryos using AAV vectors. This innovative method significantly accelerates the allele conversion process, reducing the need for animal use in line with the 3Rs principles. Congratulations to the whole team!
A warm welcome to Ruzena, who joined our lab as a research assistant. Looking forward to our future collaboration!
Warm welcome to Pavlína, who joined our lab as a research assistant. Looking forward to our future collaboration!
In collaboration with Sippl and Schutkowski labs (Halle, Germany) we used the AlphaFold models of HDAC11 for structure-based virtual screening…
Warm welcome to Júlia, who joined our lab as a research assistant. Looking forward to our future collaboration!
Congratulations to Zorka on her first first-author manuscript published in J Chem Inf Model, where we provide detailed characterization of…
In collaboration with Jan Dvorak group (Czech University of Life Sciences Prague) we used the C. elegans model organism to…
We secured funding from the Czech Science Foundation for our project aimed at understanding physiological functions of histone deacetylase 11…
Congratulation to Shivam on his successful PhD defense at the Faculty of Natural Sciences, Charles University, Prague. Great job, Dr….
Congratulations to Gargi on her first first-author manuscript published in ACS Pharmacol Transl Sci! Here we describe the engineering and…
Warm welcome to Margareta, who joined our lab as a PhD student. Her work will focus on characterization of the…
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