We are pleased to share a new collaborative study published in Computers in Biology and Medicine, led by the W. Sippl team at Martin Luther University Halle-Wittenberg. Using advanced in silico screening and molecular modeling, we identified alkyl hydrazides as a new class of highly potent HDAC11 inhibitors, with nanomolar activity confirmed in biochemical assays. Congratulations to our colleagues in Halle and all collaborators on this exciting progress toward next-generation HDAC11-targeted therapeutics!
