In their review, Zsófia and Veronika highlight studies that have successfully used computer-aided SAR analysis in lead optimization and showcase sound methodology and easily accessible in silico tools for this purpose.
In their review, Zsófia and Veronika highlight studies that have successfully used computer-aided SAR analysis in lead optimization and showcase sound methodology and easily accessible in silico tools for this purpose.
Warm welcome to Tereza, who joined our lab as an undergraduate student! She will be involved in a project aimed…
In collaboration with several groups from the US (Lipscomb University, Johns Hopkins University, The University of Connecticut Health Center) we…
Nikola passed her finals, defended thesis and got the bachelor’s degree from the Faculty of Science, Charles University, Prague! Excellent…
Dalibor defended his thesis, passed all exams and graduated (equivalent of MSc) from the Faculty of Food and Biochemical Technology…
In collaboration with groups from the Washington State University, WA, USA, we published a structure-activity relationship study mapping the importance…
Congratulation to Zorka on her manuscript in J. Med. Chem. describing unforeseen binding mode of hydroxamate-based inhibitors in the internal…
We are proud we could contribute our crystallographic expertise to the project aimed at the description of the translocation mechanism…
Jakub and Cyril have attended a conference in Nove Hrady – XIV. Discussions in Structural Molecular Biology – and presented…
We are looking for enthusiastic young colleague(s) who would be interested in joining our lab to pursue their scientific dreams…
A PhD is a step closer for Jakub, who shares the first authorship of our Protein Engineering, Design and Selection…
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