Congratulations to Gargi on her first first-author manuscript published in ACS Pharmacol Transl Sci! Here we describe the engineering and biophysical and biological characterization of bispecific T-cell engagers (BiTEs) that enable targeting PSMA-positive tumor cells by host T lymphocytes. Our 5D3-αCD3 BiTE can be viewed as a candidate molecule for the development of immunotherapeutic modalities targeting prostate cancer. Great job Gargi and you are a step closer to your PhD defense!
In collaboration with Hapuarachchige group (JHU, Baltimore, US) we used the trans-cyclooctene click chemistry to functionalize our 5D3 mAb targeting…
Time to move on… Marek is leaving our lab to meet his future life and scientific challenges as a postdoctoral…
Congratulations to Sarka on her excellent presentation at the IBT Student Days, where she was awarded first place in the…
Congratulation to Gargi on her successful PhD defense at the Immunology department, Charles University, Prague. Great job and a major…
A warm welcome to Ruzena, who joined our lab as a research assistant. Looking forward to our future collaboration!
Warm welcome to Pavlína, who joined our lab as a research assistant. Looking forward to our future collaboration!
Warm welcome to Júlia, who joined our lab as a research assistant. Looking forward to our future collaboration!
Congratulations to Zorka on her first first-author manuscript published in J Chem Inf Model, where we provide detailed characterization of…
In collaboration with Jan Dvorak group (Czech University of Life Sciences Prague) we used the C. elegans model organism to…
We secured funding from the Czech Science Foundation for our project aimed at understanding physiological functions of histone deacetylase 11…
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