In collaboration with Goldman group (Georgetown university, DC, USA) we identified galectin-3-binding protein (LG3BP) as an interaction partner of human extracellular 6-O-endosulfatases Sulf-2. LG3BP inhibits Sulf-2 activity in vitro in a concentration-dependent manner and inhibits thus the invasion of cancer cells in the tumor microenvironment.
Congratulations to Zsofia on her corresponding author manuscript aimed at the identification of novel inhibitors of human glutamate carboxypeptidase II…
Warm welcome to Mirka, who joined our lab as a research assistant. Looking forward to our future collaboration!
Warm welcome to Sarka, who joined our lab as a bachelor student. Her work will focus on establishing cell cultures…
In collaboration with Rullo lab (McMaster University, Hamilton, Canada) we developed and characterized a tunable multivalent synthetic platform that enables…
We are looking for motivated and enthusiastic researchers to join our lab as PhD candidates (PhD_1; PhD_2) or postdoctoral fellows…
In collaboration with Stanek lab (Institute of Molecular Genetics, Prague) we provide evidence that the SART3 protein is a key…
Quite a successful week! We secured another funding for our collaborative project with Pomper lab, Johns Hopkins, Baltimore. Within next…
We were successful in obtaining funding from the Czech Science Foundation for our project aimed at understanding tubulin polyglutamylation by…
Congratulation to Zorka on her 4-year collaborative grant with Villagra lab, Georgetown University, D.C., that is focused on the development…
Congratulation to Gargi! At the XXI. meeting of biochemists and molecular biologists in Brno, Gargi presented her PhD project focused…
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