We extended our in silico study carried out in collaboration with the Sippl and Schutkowski labs (Martin-Luther-University of Halle-Wittenberg, Germany) to identify nanomolar inhibitors with high selectivity towards the human HDAC11 isoform with marked cytotoxic activity against neuroblastoma cells.
In collaboration with Villagra group (George Washington Uni) and StarWise Therapeutics (A. Kozikowski) we report the developement and structural and…
Our recently developed 5D3 mAb targeting prostate-specific membrane antigen (PSMA) has been successully functionalized by collaborators from Johns Hopkins (Artemov…
We contributed our exprestise in heterologous protein expression and purification to the development of a protocol for facile allele conversion…
Congratulation to Mirek for successfully passing his Bachelor exams and defending Bachelor thesis focused on studies on membraneless organelles! Great…
Congratulations to Dariia on her successful graduation at the University of Chemistry and Technology, Prague! Dariia is heading south-east to…
In collaboration with Lansky&Braun and Neuzil groups (IBT) we reconstituted a kinesin-Trak1-mitochondria system in vitro and identified adaptor tethering as…
Congratulation to Jakub on his first-author paper in Nucl Acid Res reporting a beautiful 2.2 Å X-ray structure of human…
Congratulation to Jana on her GAUK grant focused on biochemical and structural characterization of interactions between human tubulin tyrosine-like ligase…
Congratulations to Kseniya on her prize for the best oral presentation at the ARBRE-MOBIEU international plenary meeting, Prague, 2020! One…
Congratulation to Zsofia for her first senior-author paper on prostate-specific membrane antigen (PSMA) published in J Med Chem! Here, in…
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