Congratulation to Zorka on her manuscript in J. Med. Chem. describing unforeseen binding mode of hydroxamate-based inhibitors in the internal cavity of human glutamate carboxypeptidase II. Thanks also go to Jirka, Jakub a Bara. Good job!
Congratulation to Zorka on her manuscript in J. Med. Chem. describing unforeseen binding mode of hydroxamate-based inhibitors in the internal cavity of human glutamate carboxypeptidase II. Thanks also go to Jirka, Jakub a Bara. Good job!
We are pleased to share a new study published in Cancer Letters, led by the Czech Centre for Phenogenomics (Institute…
Congratulations to Gargi Das and co-authors on their new PLOS ONE publication reporting a bispecific protein, 5D3-CP33, that activates monocytes…
We are proud to contribute to a newly published study in Cellular and Molecular Life Sciences led by Z. Cvackova…
We are delighted to share our latest publication in ACS Omega, reporting the first crystal structure of PSMA-617 and revealing…
We are pleased to announce the publication of our recent collaborative study with Hapuarachchige group (Johns Hopkins University, Baltimore) in ACS…
In close collaboration with colleagues from Masaryk University, CEITEC and Institut Curie, we have discovered a novel polyglutamylation mechanism that…
In collaboration with the Laboratory of Transgenic Models of Diseases and the Czech Centre for Phenogenomics, we have contributed to…
In collaboration with Mahboobi group (University of Regensburg, Germany) we modified Marbostat-100, an HDAC6 selective inhibitor, to significantly improve its…
We extended our in silico study carried out in collaboration with the Sippl and Schutkowski labs (Martin-Luther-University of Halle-Wittenberg, Germany)…
In collaboration with Goldman group (Georgetown university, DC, USA) we identified galectin-3-binding protein (LG3BP) as an interaction partner of human…
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