In collaboration with Jan Dvorak group (Czech University of Life Sciences Prague) we used the C. elegans model organism to study physiological roles of glutamate carboxypeptidase 2 (GCPII) orthologs. Our data shows that the orthologs affect C. elegans pharyngeal physiology, reproduction, and structural integrity and these findings could serve as leads to elucidate GCPII functions in higher organisms.
![](http://lsb.avcr.cz/wp-content/uploads/2023/12/Panska_2024_Thumb-80x80.png)